THE EFFECT OF HALOTHANE ON OXYGEN TRANSPORT IN LIVER AND BRAIN TISSUE

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Abstract
Normal rat liver and brain slice respiration was studied at 37°C by the polarographic technique of Longmuir in the presence of oxygenated solutions and with addition of clinical concentrations of halothane to the mixtures. In the presence of oxygen alone, passive and facilitated diffusion seem responsible for the transport of oxygen in both tissues. In presence of halothane, the passive diffusion is predominantly inhibited.

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