Lipoprotein profiles and serum peroxide levels of aged women consuming palmolein or oleic acid-rich sunflower oil diets

Publisher Website
Google Scholar
Abstract
Objective: To investigate the hypercholesterolemic effects of a dietary exchange between 16:0 and 18:1 while 18:2 was at relatively lower level (≈4%) in aged women with initially high total serum cholesterol (TC) and low density lipoprotein cholesterol (LDL-C) values and with high intakes of dietary cholesterol. Design: Subjects were assigned to two consecutive 28 d periods. In the first period all subjects followed an oleic acid-rich diet in the form of oleic acid-rich sunflower oil. This was followed by a second period rich in palmitic acid in the form of palmolein. Nutrient intakes, serum lipids, lipoproteins, antioxidant vitamins, peroxides and LDL-peroxides were measured at two dietary periods. Setting: Instituto de Nutrición y Bromatología (CSIC), Departamento de Nutrición y Bromatología I (Nutrición) and Sección Departamental de Química Analítica, Universidad Complutense, Madrid, Spain. Results: The palmolein period led to an increase in TC (PPPPPPP=0.06) only in normocholesterolemics. Serum and LDL-peroxides tended to be higher in women with TC≥6.21 mmol/L than in women with TC<6.21 mmol/L, but palmolein decreased serum and LDL-peroxide in hypercholesterolemics more than in the normocholesterolemics, resulting in serum and LDL-peroxide levels which theoretically are more adequate. Conclusions: Though palmolein increased LDL-C concentrations, it better protected LDL particles, mainly in women with high TC, against peroxidation than did oleic acid-rich sunflower oil. Sponsorship: This study was supported by the Spanish Comision Interministerial de Ciencia Y Tecnología (CICYT) Project No ALI-92-0289-C02-01.

This publication has 0 references indexed in Scilit: