Reducing Allogenic Blood Transfusions during Pediatric Cranial Vault Surgical Procedures:

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Abstract
Almost all patients who undergo major craniosynostosis corrections receive allogenic blood transfusions. This study of intraoperative blood salvage was undertaken in an attempt to further reduce the need for blood transfusions and to enhance the safety of these complex procedures. This prospective nonrandomized series included 60 consecutive children undergoing major cranial vault remodeling, primarily for treatment of craniosynostosis (single-suture and syndromic). A single craniofacial surgeon performed all operations, using a cell-saver equipped with a 55-cc pediatric bowl. The average age of the patients in this series was 4 years (33 of 60 patients were less than 18 months of age), and the average length of the surgical procedure was 196 minutes. Fifty-three percent were primary procedures and 47 percent were secondary. The mean estimated blood loss was 356 cc (19 cc/kg, or 28.5 percent of the estimated total blood volume). An average of 110 cc of cell-saver blood (range, 5 to 900 cc), or 7.8 percent of the patient's estimated total blood volume (approximately 15 percent, accounting for hemoconcentration of the cell-saver blood), was recycled for transfusion. No statistically significant factors (primary versus secondary procedure, diagnosis, age, or weight) were identified as predictive indicators for the use of this technology. Although 59 of 60 patients received transfusions, only 18 (30 percent) received allogenic blood (average, approximately 140 cc). There were no complications associated with the use of the cell-saver device. Use of the cell-saver during major craniosynostosis repair seemed to be safe and was associated with an extremely low allogenic blood transfusion rate.