Comparison of the potency, kinetics and voltage-dependency of a series of uncompetitive NMDA receptor antagonists in vitro with anticonvulsive and motor impairment activity in vivo
- 1 October 1995
- journal article
- Published by Elsevier in Neuropharmacology
- Vol. 34 (10) , 1239-1258
- https://doi.org/10.1016/0028-3908(95)00092-k
Abstract
No abstract availableKeywords
This publication has 42 references indexed in Scilit:
- The excitatory amino acid antagonist d-CPP-ene (SDZ EAA-494) in patients with epilepsyEpilepsy Research, 1993
- Antiparkinsonian drugs memantine and trihexyphenidyl potentiate the anticonvulsant activity of valproate against maximal electroshock-induced seizuresNeuropharmacology, 1992
- The NMDA Receptor, NMDA Antagonists and Epilepsy TherapyDrugs, 1992
- Biological profile of the metabolites and potential metabolites of the anticonvulsant remacemideEpilepsy Research, 1992
- Intra- and extracellular changes of amino acids in the cerebral cortex of the neonatal rat during hypoxic-ischemiaDevelopmental Brain Research, 1991
- Comparative Effect of Transient Global Ischemia on Extracellular Levels of Glutamate, Glycine, and γ‐Aminobutyric Acid in Vulnerable and Nonvulnerable Brain Regions in the RatJournal of Neurochemistry, 1991
- Effects of the 1-amino-adamantanes at the MK-801-binding site of the NMDA-receptor-gated ion channel: a human postmortem brain studyEuropean Journal of Pharmacology: Molecular Pharmacology, 1991
- Modulation of the NMDA receptor by polyaminesLife Sciences, 1991
- Elevation of the Extracellular Concentrations of Glutamate and Aspartate in Rat Hippocampus During Transient Cerebral Ischemia Monitored by Intracerebral MicrodialysisJournal of Neurochemistry, 1984
- Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reactionBiochemical Pharmacology, 1973