Chemotherapy of Experimental (Murine) Clostridium perfringens Type A Gas Gangrene
- 1 January 1988
- journal article
- research article
- Published by S. Karger AG in Chemotherapy
- Vol. 34 (6) , 472-477
- https://doi.org/10.1159/000238611
Abstract
Five antimicrobial drugs (ciprofloxacin, clindamycin, imipenem, penicillin G, and rifampin) were examined for therapeutic efficacy in a murine model gas gangrene due to Clostridium perfringens type A, following infection with large bacterial inocula. Imipenem was effective against all 6 strains of C. perfringens; conversely, penicillin G failed against these 6 strains. Ciprofloxacin, clindamycin and rifampin occupied intermediate positions.This publication has 6 references indexed in Scilit:
- Growth curves of clostridium perfringens in schaedler and brain heart infusion brothsZentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Series A: Medical Microbiology, Infectious Diseases, Virology, Parasitology, 1987
- Comparison of single and combination antimicrobial agents for prevention of experimental gas gangrene caused by Clostridium perfringensAntimicrobial Agents and Chemotherapy, 1987
- Comparison of Clindamycin, Rifampin, Tetracycline, Metronidazole, and Penicillin for Efficacy in Prevention of Experimental Gas Gangrene Due to Clostridium perfringensThe Journal of Infectious Diseases, 1987
- Clostridium perfringens Type AChemotherapy, 1986
- Susceptibility of Clostridium perfringens Type A to 23 Antimicrobial DrugsChemotherapy, 1986
- Beitrag zur kollektiven Behandlung pharmakologischer ReihenversucheNaunyn-Schmiedebergs Archiv für experimentelle Pathologie und Pharmakologie, 1931