A Single-Step Synthesis of Tamoxifen Using Palladium-Catalyzed Cross-Coupling
- 1 January 1987
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1987 (09) , 816-817
- https://doi.org/10.1055/s-1987-28084
Abstract
The synthesis of tamoxifen, a biologically active tetrasubstituted olefin was achieved via palladium-catalyzed cross-coupling of vinylmetal with 2-(4-bromophenoxy)-1-dimethylaminoethane.Keywords
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