New antibiotics from genetically engineered actinomycetes. I. 2-norerythromycins, isolation and structural determinations.
- 1 January 1987
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 40 (8) , 1115-1122
- https://doi.org/10.7164/antibiotics.40.1115
Abstract
Novel macrolide antibiotics have been isolated from a genetically manipulated actinomycete. The major components produced have been isolated and identified as 2-norerythromycins, A, B, C and D by mass spectrometry and extensive 1D and 2D NMR experiments.This publication has 2 references indexed in Scilit:
- Production of new hybrid antibiotics, mederrhodins A and B, by a genetically engineered strainAntimicrobial Agents and Chemotherapy, 1986
- An analysis of the 1H and 13C n.m.r. spectra of erythromycin a using two-dimensional methodsJournal of the Chemical Society, Perkin Transactions 1, 1985