THE INCIDENCE OF POSITIVE ESTROGEN AND PROGESTERONE RECEPTORS IN BREAST-CANCER OF GREEK WOMEN

  • 1 January 1981
    • journal article
    • research article
    • Vol. 1  (4) , 195-197
Abstract
Estrogen and progesterone receptors were determined in breast tumors of 80 Greek women. Estrogen-positive receptors were found in 84.6% of the premenopausal (n = 39) and 85.4% of the postmenopausal (n = 41) patients while progesterone-positive receptors were found in 71.8% of these women, respectively. In combination, 69.2% of the premenopausal women had both receptors detectable, 15.4% had estrogen-positive and progesterone-negative and 2.6% had estrogen negative and progesterone-positive while 12.8 had no detectable receptors. This incidence in postmenopausal women was 51.2, 34.2, 0.0, 14.6%, respectively. The ratio of progesterone to estradiol receptor concentration was 7.6 in the pre- and 1.7 in the postmenopausal group (P < 0.05). The incidence of positive receptors in Greek women with breast cancer is similar to that of other Western populations. [Determination of receptors for sex steroid hormones in women with breast cancer is a relatively reliable means to predict the course of the disease and the effectiveness of endocrine treatment.].