DUCHENNE MUSCULAR-DYSTROPHY (DMD) IN A FEMALE WITH AN X-AUTOSOME TRANSLOCATION - FURTHER EVIDENCE THAT THE DMD LOCUS IS AT XP21

  • 1 January 1981
    • journal article
    • research article
    • Vol. 33  (4) , 513-518
Abstract
Duchenne muscular dystrophy in a female with a de novo t(X;5)(p21;q35) translocation is described. The similarities between this patient and 4 previously reported females with Duchenne muscular dystrophy are discussed. The locus for Duchenne muscular dystrophy is at Xp21; this site may be particularly susceptible both to chromosome breakage and exchange and to gene mutation.