Clinical automatic control of neuromuscular blockade
- 1 March 1986
- journal article
- Published by Wiley in Anaesthesia
- Vol. 41 (3) , 316-320
- https://doi.org/10.1111/j.1365-2044.1986.tb12796.x
Abstract
A simple feedback control technique has been used to automatically deliver pancuronium to anaesthetised surgical patients. The dosage rate is automatically adjusted at 10-second intervals, according to the measured evoked, rectified, integrated electromyogram. When set to demand 80 percent blockade, in 40 patients, the controller maintained blockade at a steady mean level of 72.9 percent (consuming pancuronium at a mean rate of 0.47 microgram/kg/minute). The main clinical practical problems involved protection against electrical noise and the need to spend time setting up the equipment.Keywords
This publication has 1 reference indexed in Scilit:
- Closed-loop control of muscle relaxation during surgeryClinical Physics and Physiological Measurement, 1980