Polynucleotides. XXII(1). Synthesis and properties of poly 7-deazainosinic acid
Open Access
- 1 January 1974
- journal article
- research article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 1 (1) , 53-61
- https://doi.org/10.1093/nar/1.1.53
Abstract
Poly 7-deazainosinic acid has been prepared by the deamination and phosphorylation of tubercidin and the nucleoside diphosphate was polymerised using polynucleotide phosphorylase. The polymer has similar physical properties to poly(I), but has alow thermal stability in the double-stranded complex with poly(C). Poly(7-deaza I), in contrast, forms a more stable triple-stranded complex with poly(A) than 2 poly (I) poly(A), presumably due to the higher pK value.Keywords
This publication has 8 references indexed in Scilit:
- Synthesis and coding properties of poly(c1A), poly(c3A), poly(c7A) and poly(h6A)Biochemical and Biophysical Research Communications, 1973
- Polynucleotides XV. Synthesis and properties of polynucleotides containing
dimethylguanylic acid residues in polyinosinate and polyadenylate chainsBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1972 - PolynucleotidesBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1972
- Synthesis and properties of poly(2-methylthioinosinic acid)Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1972
- Synthesis and properties of polyribonucleotides containing N2-methyl- and N2-dimethylguanylic acid in polyguanylic acidBiochemistry, 1971
- Some physical properties of poly 7-deazaadenylic acid (poly Tubercidin phosphoric acid)Journal of Molecular Biology, 1968
- Inducers of interferon and host resistance, V. In vitro studies.Proceedings of the National Academy of Sciences, 1968
- A displacement reaction between a polynucleotide helix and a random coilJournal of Molecular Biology, 1962