Synthesis of the pyrrolizidine base, (±)-supinidine
- 1 January 1979
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 7,p. 1734-1735
- https://doi.org/10.1039/p19790001734
Abstract
A novel method for the conversion of saturated pyrrolizidine esters into their 1,2-didehydro-derivatives has been established. The unsaturation is introduced by phenylselenenylation α to an ester function, followed by fragmentation of the derived seleno-derivative. Using this technique, (±)-supinidine (1) has been synthesized.This publication has 1 reference indexed in Scilit:
- A new synthesis of the pyrrolizidine alkaloids (.+-.)-isoretronecanol and (.+-.)-trachelanthamidineThe Journal of Organic Chemistry, 1977