EVALUATION OF XYLAZINE IN CAMELS

  • 1 January 1980
    • journal article
    • research article
    • Vol. 177  (9) , 875-878
Abstract
When xylazine was given i.m. to 12 apparently healthy adult camels (C. dromedarius) at the rate of 0.4 mg/kg body wt, mean values for onset of weak time, down time and time until recovery were 8.6 .+-. 1.1, 10.5 .+-. 0.6 and 150 .+-. 56.9 min, respectively. Mild salivation, drooping of lower lips and relaxation of neck were observed at mean times of 15.3 .+-. 4.9, 11.0 .+-. 1.7 and 22.7 .+-. 3.9 min, respectively. Analgesic effects remained for 60-90 min. Hemocytologic changes were not statistically significant. Marked hyperglycemia was observed at 30 min after xylazine administration. Hypotension from 30-60 min after xylazine administration was not correlated with elevated central venous pressure or with bradycardia. ECG revealed 1st-degree atrioventricular block, sinoatrial block, sinus arrhythmia and wandering pacemaker in sinoatrial node, which were attributed to vagal stimulation. Primary T-wave changes and ST segment elevation also were observed. Xylazine used at the same dosage in 13 clinical cases involving surgery of short duration was a satisfactory sedative, analgesic and muscle relaxant.

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