Camptothecin Resistance Related to Drug-induced Down-Regulation of Topoisomerase I and to Steps Occurring after the Formation of Protein-linked DNA Breaks

This publication has 22 references indexed in Scilit:

• Mechanism of Action of Camptothecin
  Annals of the New York Academy of Sciences, 1996
• 9-nitro-camptothecin delays growth of U-937 leukemia tumors in nude mice and is cytotoxic or cytostatic for human myelomonocytic leukemia lines in vitro
  European Journal of Haematology, 1993
• Characterization of camptothecin-resistant chinese hamster lung cells
  Biochemical Pharmacology, 1992
• Camptothecin cytotoxicity in mammalian cells is associated with the induction of persistent double strand breaks in replicating DNA
  Nucleic Acids Research, 1991
• The S-phase cytotoxicity of camptothecin
  Experimental Cell Research, 1991
• Rapid induction of c-fos transcription reveals quantitative linkage of RNA polymerase II and DNA topoisomerase I enzyme activities
  Cell, 1990
• Nonproductive Rearrangement of DNA Topoisomerase I and II Genes: Correlation With Resistance to Topoisomerase Inhibitors
  JNCI Journal of the National Cancer Institute, 1989
• DNA Topoisomerase Poisons As Antitumor Drugs
  Annual Review of Biochemistry, 1989
• Characterization of a mammalian mutant with a camptothecin-resistant DNA topoisomerase I.
  Proceedings of the National Academy of Sciences, 1987
• New views of the biochemistry of eucaryotic DNA replication revealed by aphidicolin, an unusual inhibitor of DNA polymerase α
  Cell, 1981