The Activity of Leukocyte NADPH Oxidase: Regulation by p47PHOXCysteine and Serine Residues
- 1 February 2002
- journal article
- research article
- Published by Mary Ann Liebert Inc in Antioxidants and Redox Signaling
- Vol. 4 (1) , 35-38
- https://doi.org/10.1089/152308602753625834
Abstract
The leukocyte NADPH oxidase is regulated chiefly by phosphorylation of the serines of p47PHOX, one of its cytosolic subunits. Its activity is also regulated, however, by the four cysteines of the same subunit, as indicated by the replacement of those cysteines by alanines.Keywords
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