Bacterial competition as a means of preventing neonatal diarrhea in pigs

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Abstract
Baby pigs orally inoculated with a porcine strain of enterotoxigenic Escherichia coli (K88+,Ent+) showed signs of depression, severe diarrhea and sometimes death. Few, if any, signs of illness occurred if baby pigs were 1st inoculated with a K88-possessing non-enterotoxin-producing strain of E. coli. [This protection was probably due to the prevention of adsorption of the enterotoxigenic strain by the prior adsorption of the nonenterotogigenic strain on the small intestine cells.].