Holoprosencephaly and interstitial deletion of 2(p2101p2109)

Abstract
We report on a girl with holoprosencephaly and a small, de novo interstitial deletion of most of band 2(p21). The similarity between the cytogenetic findings and CNS malformations in our patient and those recently reported by Münke et al. [Am J Med Genet 30:929–938, 1988] suggests a phenotypic relationship between deletion of this band and holoprosencephaly.