Behavioral Effects in Monkeys of Racemates of Two Biologically Active Marijuana Constituents
- 28 June 1968
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 160 (3835) , 1467-1469
- https://doi.org/10.1126/science.160.3835.1467
Abstract
Both dl-Δ8- and dl-Δ9-tetrahydrocannabinol produced marked alterations of behavior in rhesus and squirrel monkeys. Squirrel monkeys appeared to have visual hallucinations. Continuous avoidance behavior of squirrel monkeys was stimulated by both drugs, but high doses of dl-Δ9-tetrahydrocannabinol also caused depression after the stimulant phase. Complex behavior involving memory and visual discrimination in rhesus monkeys was markedly disrupted by both drugs.Keywords
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