Risks and Benefits of Antiarrhythmic Therapy

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Abstract
Drug treatment of cardiac arrhythmias is not uniformly effective and frequently causes side effects. Recently, new data have become available that more clearly delineate the risks of antiarrhythmic-drug therapy. At the same time, establishing a benefit of treatment with these drugs has proved difficult. The potential benefits of antiarrhythmic therapy -- reductions in mortality or in symptoms related to arrhythmias -- as well as the potential risks are outlined in Table 1. In this review I shall consider the available data defining these risks and benefits (which have usually been delineated in specific groups of patients using specific drugs), the risk . . .

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