Confounding in Health Research
Top Cited Papers
- 1 May 2001
- journal article
- review article
- Published by Annual Reviews in Annual Review of Public Health
- Vol. 22 (1) , 189-212
- https://doi.org/10.1146/annurev.publhealth.22.1.189
Abstract
▪ Abstract Consideration of confounding is fundamental to the design, analysis, and interpretation of studies intended to estimate causal effects. Unfortunately, the word confounding has been used synonymously with several other terms, and it has been used to refer to at least four distinct concepts. This paper provides an overview of confounding and related concepts based on a counterfactual model of causation. In this context, which predominates in nonexperimental research, confounding is a source of bias in the estimation of causal effects. Special attention is given to the history of definitions of confounding, the distinction between confounding and confounders, problems in the control of confounding, the relations of confounding to exchangeability and collapsibility, and confounding in randomized trials.Keywords
This publication has 79 references indexed in Scilit:
- Identification of Causal Effects Using Instrumental VariablesJournal of the American Statistical Association, 1996
- Causal Inference in Infectious DiseasesEpidemiology, 1995
- Randomization, Statistics, and Causal InferenceEpidemiology, 1990
- Choosing Among Alternative Nonexperimental Methods for Estimating the Impact of Social Programs: The Case of Manpower TrainingJournal of the American Statistical Association, 1989
- A graphical approach to the identification and estimation of causal parameters in mortality studies with sustained exposure periodsJournal of Chronic Diseases, 1987
- Statistics and Causal InferenceJournal of the American Statistical Association, 1986
- A new approach to causal inference in mortality studies with a sustained exposure period—application to control of the healthy worker survivor effectMathematical Modelling, 1986
- Collapsibility and Response Variables in Contingency TablesBiometrika, 1983
- Randomization models for the Matched and Unmatched 2 × 2 TablesBiometrika, 1973
- Pertinency of an extraneous variableJournal of Chronic Diseases, 1967