Role of Computed Tomography in the Evaluation of Therapy in Cases of Cranial Metastatic Neuroblastoma

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Abstract
Cranial computed tomography (CT) is an extremely useful diagnostic modality in the evaluation and follow-up of children undergoing treatment for metastatic neuroblastoma. Information regarding the location, extent of the cranial metastatic lesions and their response to treatment was provided by sequential CT examinations in 3 patients. Computed tomography showed nonneoplastic lesions in 4 patients treated by parenteral chemotherapy alone using vincristine and cytoxan. These lesions probably were neurotoxic sequelae of the prolonged chemotherapy.