Bursal origin of bone marrow cells with competence for antibody formation.
- 1 July 1972
- journal article
- Vol. 23 (1) , 107-11
Abstract
The impaired antibody response of neonatally bursectomized chickens was restored by bone marrow cells from normal—but not from bursectomized—syngeneic donors. Chimaerism of donor cells in the recipients was demonstrated using the sex chromosomal marker. Attempts to substitute autologous bursal cell suspensions for the bursa in situ were unsuccessful. It is concluded that B lymphocytes in chicken bone marrow have matured in the bursa.This publication has 17 references indexed in Scilit:
- Cellular Events in the Induction and Loss of Tolerance to Pneumococcal PolysaccharidesImmunological Reviews, 1972
- SUPPRESSION OF GRAFT-VERSUS-HOST-REACTIVE LYMPHOCYTES BY HETEROLOGOUS ANTITHYMUS SERUM IN VITROTransplantation, 1971
- Antigen Binding Cells in Embryonic Chicken Bursa and ThymusNature New Biology, 1971
- A system for lymphocytes in the mouseProceedings of the Royal Society of London. B. Biological Sciences, 1971
- FUNCTIONAL DEFICIENCY OF AUTOLOGOUS IMPLANTS OF THE BURSA OF FABRICIUS IN CHICKENSTransplantation, 1971
- Impairment of humoral antibody response in neonatally thymectomized and irradiated chickensEuropean Journal of Immunology, 1971
- MATURATION OF HEMOLYSIN-PRODUCING CELL CLONESThe Journal of Experimental Medicine, 1970
- CELLS INVOLVED IN THE IMMUNE RESPONSEThe Journal of Experimental Medicine, 1969
- Experimental studies on the development of the bursa of FabriciusDevelopmental Biology, 1966
- Karyotype studies on Gallus domesticusChromosoma, 1965