Mechanism of action of eukaryotic topoisomerase II and drugs targeted to the enzyme
- 1 October 1998
- journal article
- review article
- Published by Elsevier in Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression
- Vol. 1400 (1-3) , 139-154
- https://doi.org/10.1016/s0167-4781(98)00132-8
Abstract
No abstract availableKeywords
This publication has 141 references indexed in Scilit:
- Type II DNA topoisomerasesCurrent Opinion in Structural Biology, 1998
- Antitopoisomerase drug action and resistancePublished by Elsevier ,1996
- DNA topoisomerase-trapping antitumour drugsEuropean Journal Of Cancer, 1992
- Mode of action of topoisomerase II-targeting agents at a specific DNA sequence: Uncoupling the DNA binding, cleavage and religation eventsJournal of Molecular Biology, 1992
- Effects of antineoplastic drugs on the post-strand-passage DNA cleavage/religation equilibrium of topoisomerase IIBiochemistry, 1991
- DNA topoisomerase II is required for formation of mitotic chromosomes in Chinese hamster ovary cells: studies using the inhibitor 4'-demethylepipodophyllotoxin 9-(4,6-O-thenylidene-.beta.-D-glucopyranoside)Biochemistry, 1990
- Characterization of the interaction between topoisomerase II and DNA by transcriptional footprintingJournal of Molecular Biology, 1990
- Purification and characterization of an altered topoisomerase II from a drug-resistant Chinese hamster ovary cell lineBiochemistry, 1989
- Role of divalent cation in topoisomerase II mediated reactionsBiochemistry, 1987
- The interaction between nuclear topoisomerase II activity from human leukemia cells, exogenous DNA, and 4′-(9-acridinylamino) methanesulfon-m-anisidide (m-AMSA) or 4-(4,6-0-ethylidene-β-D-glucopyranoside) (VP-16) indicates the sensitivity of the cells to the drugsBiochemical and Biophysical Research Communications, 1987