Antibacterial Property of Tetramethyl-Pyrazine from the Stem of Jatropha podagrica

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Abstract
The methanolic extract of stem of Jatropha podagrica Hook has demonstrated antibacterial activity against only gram positive microorganisms. Fractionation of this extract resulted in a number of active fractions. One of them contained the amide alkaloid tetramethylpyrazine. The presence of this alkaloid has previously not been reported in any Jatropha species. The structures of [the] other active compounds are still being determined.