Hypervitaminosis A in a patient with alopecia receiving renal dialysis

Publisher Website
Google Scholar
Abstract
A patient with gradually increasing hair loss was undergoing long-term renal dialysis. Questioning revealed that her supplemental vitamin program had contained vitamin A only to that extent it was included in a portion of multivitamins taken in conventional amounts for approximately 3 yr. Her serum vitamin A level was 140 .mu.g/dl (a normal level is 20-80 .mu.g/dl). Chronic renal disease may result in a state of relative hypervitaminosis A. This is compounded in renal dialysis by failure to remove vitamin A. The administration of low-dose supplemental vitamin A preparations in this select population is discussed with respect to current concepts of vitamin A metabolism in renal disease.