The Morphology of Simian Immunodeficiency Virus as Shown by Negative Staining Electron Microscopy
- 1 August 1989
- journal article
- research article
- Published by Microbiology Society in Journal of General Virology
- Vol. 70 (8) , 2215-2219
- https://doi.org/10.1099/0022-1317-70-8-2215
Abstract
Negative staining electron microscopy was used to study sucrose gradient-purified preparations of the simian immunodeficiency virus (SIVmac251). Both isolated and aggregated virus particles were observed together with some free-lying virus cores. The cores were 110 nm long and 25 to 50 nm wide and were mainly conical or wedge-like in shape. Surface projections were seen on the envelope membrane of many of the virus particles; the knobs were approximately 6 nm in length, 10 nm wide and from an end-on view they had a Y or triangular-shaped morphology.This publication has 2 references indexed in Scilit:
- Prevalence of antibodies to 3 retroviruses in a captive colony of macaque monkeysInternational Journal of Cancer, 1988
- Humoral immune responses to T cell tropic retrovirus simian T lymphotropic virus type III in monkeys with experimentally induced acquired immune deficiency-like syndrome.Journal of Clinical Investigation, 1986