Cell functions inDrosophila oogenesis

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Abstract
We are studyingDrosophila oogenesis by analysing at genetic and molecular levels several female-sterile mutations. Some (hold up, wavoid-like andabnormal oocyte) have been isolated by L. Sandler in region 32 of the second chromosome; others have been isolated by us and their phenotype is presented for the first time in this paper. We performed chromosome walking in 32D-32E-F (250 Kb) and 32A-B (100 Kb) and in the last years we molecularly identified several genes with specific maternal expression patterns. We will review here our studies on two of these genes: the Vitelline Membrane Protein gene 32E and the gene coding for a receptor form of Guanylate Cyclase.