Synthesis of Novel Four-Membered Ring Amino Acids as Modulators of theN-Methyl-D-Aspartate(NMDA) Receptor Complex
- 1 January 1991
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 1991 (11) , 783-784
- https://doi.org/10.1055/s-1991-20873
Abstract
The first syntheses of three novel four-membered ring amino acids (3-aminooxetane-3-carboxylic acid, 3-aminoazetidine-3-carboxylic acid and 3-aminothietane-3-carboxylic acid), starting from 1-chloro-2,3-epoxypropane, are reported together with a summary of their biological actions at the NMDA receptor-ion channel complex.Keywords
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