A Study on the Mechanism of the Hypotensive Activity ofBuddleja asiatica(Newarpati)

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Abstract
The plant Buddleja asiatica Loureiro (family Buddlejiaceae) is known as “Newarpati” in the vernacular. It grows abundantly in the sub-Himalayan hill tracts. It has been described in the ancient medical literature to be useful in a variety of skin disorders and has also been used as an abortifacient (Chopra et al., 1956). Recently Singh (1977), while studying its antifertility and general pharmacological activities, found that the alcoholic extract obtained from the leaves of this plant produced a persistent and prolonged fall of blood pressure in pentobarbitone-anaesthetised dogs and cats. The present study was carried out to analyze the mechanisms involved for this hypotensive response.

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