Crosslinking of DNA to nuclear lamina proteins by UV irradiation in vivo
- 1 July 1987
- journal article
- research article
- Published by Wiley in Journal of Cellular Biochemistry
- Vol. 34 (3) , 163-168
- https://doi.org/10.1002/jcb.240340303
Abstract
We have been able to demonstrate that a fraction of DNA becomes crosslinked to nuclear lamina shells isolated from Ehrlich ascites tumour cells irradiated with UV light. Terminal labeling of short DNA fragments covalently attached to proteins reveals that DNA has become crosslinked to all three lamins and to a protein comigrating with vimentin.Keywords
This publication has 17 references indexed in Scilit:
- Association of DNA with the nuclear lamina in Ehrlich ascites tumor cellsJournal of Cellular Biochemistry, 1986
- Isolation and characterization of nuclear lamina from ehrlich ascites tumor cellsJournal of Cellular Biochemistry, 1986
- The organizational fate of intermediate filament networks in two epithelial cell types during mitosis.The Journal of cell biology, 1985
- Spontaneous formation of nucleus-like structures around bacteriophage DNA microinjected into Xenopus eggsPublished by Elsevier ,1983
- Non-histone proteins and long-range organization of HeLa interphase DNAJournal of Molecular Biology, 1982
- hnRNA and its attachment to a nuclear protein matrix.The Journal of cell biology, 1981
- The nuclear shell in hela cell nuclei: Whole-mount electron microscopy of the dissociated and isolated nuclear peripheryJournal of Ultrastructure Research, 1980
- Metrizamide, a new density‐gradient mediumFEBS Letters, 1975
- Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Nature, 1970
- Chromosomal Localization of Mouse Satellite DNAScience, 1970