Anti-neutrophil cytoplasmic autoantibodies in a child with pauci-immune necrotizing and crescentic glomerulonephritis

1 January 1991

journal article
case report
Published by Springer Nature in Pediatric Nephrology

Vol. 5 (3) , 296-299
https://doi.org/10.1007/bf00867482

Abstract

We report a case of pauci-immune, necrotizing and crescentic glomerulonephritis in a 10-year-old child initially thought to have Henoch-Schönlein purpura. The diagnosis of a Wegener's granulomatosis-microscopic polyarteritis disorder was made on the basis of clinical presentation and a positive anti-neutrophil cytoplasmic auto-antibody (ANCA). This case illustrates the usefulness of the ANCA in the diagnosis and management of childhood vasculitides.

Keywords

This publication has 18 references indexed in Scilit:

Association between active Wegener's granulomatosis and anticytoplasmic antibodies
Archives of internal medicine (1960), 1989
Antineutrophil cytoplasm antibodies in Kawasaki disease.
Archives of Disease in Childhood, 1989
Anticytoplasmic Autoantibodies in the Diagnosis and Follow-Up of Wegener's Granulomatosis
Mayo Clinic Proceedings, 1989
Antineutrophil cytoplasm antibody in crescentic glomerulonephritis.
Archives of Disease in Childhood, 1988
Anti-Neutrophil Cytoplasmic Autoantibodies with Specificity for Myeloperoxidase in Patients with Systemic Vasculitis and Idiopathic Necrotizing and Crescentic Glomerulonephritis
New England Journal of Medicine, 1988
PROSPECTIVE STUDY OF RADIOIMMUNOASSAY FOR ANTIBODIES AGAINST NEUTROPHIL CYTOPLASM IN DIAGNOSIS OF SYSTEMIC VASCULITIS
The Lancet, 1987
Severe Glomerulonephritis with Late Emergence of Classic Wegenerʼs Granulomatosis
Medicine, 1987
Wegener granulomatosis in pediatric patients
The Journal of Pediatrics, 1985
AUTOANTIBODIES AGAINST NEUTROPHILS AND MONOCYTES: TOOL FOR DIAGNOSIS AND MARKER OF DISEASE ACTIVITY IN WEGENER'S GRANULOMATOSIS
The Lancet, 1985
Wegener granulomatosis in childhood: Prolonged survival following cytotoxic therapy
The Journal of Pediatrics, 1977