Theoretical approaches to drug design and biological activity: Critical comments to the use of mathematical methods applied to univariate and multivariate quantitative structure-activity relationships (QSAR)
- 1 January 1982
- journal article
- Published by Wiley in Medicinal Research Reviews
- Vol. 2 (1) , 93-121
- https://doi.org/10.1002/med.2610020106
Abstract
No abstract availableThis publication has 21 references indexed in Scilit:
- Relationships between chemical structure and biological activity modeled by SIMCA pattern recognitionBioorganic Chemistry, 1980
- Principal component regression analysis applied in structure‐activity relationships. 1. selective dihydrofolic acid reductase inhibitorsBiometrical Journal, 1980
- Discriminant-analytical investigation on the structural dependence of hyperglycemic and hypoglycemic activity in a series of substituted o-toluenesulfonylthioureas and o-toluenesulfonylureasJournal of Medicinal Chemistry, 1979
- Multidimensional Analysis of the Effects of Organic Molecules, Metabolic Inhibitors and Drugs on Biochemical ResponsesBiometrical Journal, 1977
- Die Auswertung multivariater Daten: Multivariate Varianzanalyse ‐ angewandt zur pharmakologischen Screening‐AnalyseBiometrische Zeitschrift, 1975
- Die Wirkung von intraventrikulär applizierteml-Glutamat auf die Akquisition und Extinktion einer instrumentellen Konditionierungsreaktion bei RattenCellular and Molecular Life Sciences, 1974
- A note on the autoregressive process during the conditioned avoidance response in ratsCellular and Molecular Life Sciences, 1974
- Die Auswertung multivariater Daten: HOTELLINGST2‐TestBiometrische Zeitschrift, 1974
- Strategy in drug design. Cluster anlysis as an aid in the selection of substituentsJournal of Medicinal Chemistry, 1973
- Nature of the ortho effect. II. Composition of the Taft steric parametersJournal of the American Chemical Society, 1969