SERUM BETA-2-MICROGLOBULIN IN AFRICAN BURKITT TUMOR, NASOPHARYNGEAL CARCINOMA AND CONTROLS

  • 1 January 1981
    • journal article
    • research article
    • Vol. 35  (3) , 104-107
Abstract
Serum .beta.2-microglobulin measurements were made in Burkitt lymphoma and nasopharyngeal carcinoma in Africans and infectious mononucleosis in Europeans. There was a significant increase of .beta.2-microglobulin levels in cases with active Burkitt tumor compared to those in remission, but young West African children have higher levels than Caucasians. Nasopharyngeal carcinoma can be associated with a raised .beta.2-microglobulin but the distribution is similar to that seen in other head and neck cancers. In 27 cases of infectious mononucleosis 74% have raised levels of serum .beta.2-microglobulin. The mechanism of production of high serum .beta.2-microglobulin levels in rural African children is unknown.

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