Glycogen and Succinic Dehydrogenase in Wound Healing of the Oral Mucosa of the Rat

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Abstract
Summary Morphological healing in the oral mucosa as indicated by hematoxylin and eosin preparations precedes histochemical healing. Epithelial proliferation in wound healing appears to be associated with the disappearance of glycogen. Lack of epithelial growth appears to be manifested by an accumulation of glycogen. The metabolism of the epithelial basal cells as indicated by the presence of succinic dehydrogenase appears to be related to epithelial and connective tissue continuity. Its presence in the basal cells of the epithelium confirms that metabolic activity is highest where there is no visible glycogen. Injury to the epithelium of the mucous membrane causes glycogen accumulation similar to that in skin. Succinic dehydrogenase is distributed in the mucous membrane of the anterior palate of the rat much as it is in the skin.

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