Creation of an Enantioselective Hydrolase by Engineered Substrate-Assisted Catalysis

This publication has 17 references indexed in Scilit:

• Biotransformations in Organic Chemistry
  Published by Springer Nature ,2000
• Creation of a Synthetically Useful Lipase with Higher Than Wild-Type Enantioselectivity and Maintained Catalytic Activity
  Organic Letters, 1999
• Molecular Basis for Enantioselectivity of Lipase from Pseudomonas cepacia toward Primary Alcohols. Modeling, Kinetics, and Chemical Modification of Tyr29 to Increase or Decrease Enantioselectivity
  The Journal of Organic Chemistry, 1999
• Directed evolution of an esterase for the stereoselective resolution of a key intermediate in the synthesis of epothilones
  Biotechnology & Bioengineering, 1998
• One Biocatalyst–Many Applications: The Use of Candida Antarctica B-Lipase in Organic Synthesis
  Biocatalysis and Biotransformation, 1998
• Crystallographic and molecular-modeling studies of lipase B from Candida antarctica reveal a stereospecificity pocket for secondary alcohols
  Biochemistry, 1995
• The sequence, crystal structure determination and refinement of two crystal forms of lipase B from Candida antarctica
  Structure, 1994
• Lipases fromRhizomucor miehei andHumicola lanuginosa: Modification of the lid covering the active site alters enantioselectivity
  Protein Journal, 1993
• Engineering Enzyme Specificity by "Substrate-Assisted Catalysis"
  Science, 1987
• Serine Proteases: Structure and Mechanism of Catalysis
  Annual Review of Biochemistry, 1977