ENCODE whole-genome data in the UCSC Genome Browser: update 2012
Top Cited Papers
Open Access
- 9 November 2011
- journal article
- research article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 40 (D1) , D912-D917
- https://doi.org/10.1093/nar/gkr1012
Abstract
The Encyclopedia of DNA Elements (ENCODE) Consortium is entering its 5th year of production-level effort generating high-quality whole-genome functional annotations of the human genome. The past year has brought the ENCODE compendium of functional elements to critical mass, with a diverse set of 27 biochemical assays now covering 200 distinct human cell types. Within the mouse genome, which has been under study by ENCODE groups for the past 2 years, 37 cell types have been assayed. Over 2000 individual experiments have been completed and submitted to the Data Coordination Center for public use. UCSC makes this data available on the quality-reviewed public Genome Browser (http://genome.ucsc.edu) and on an early-access Preview Browser (http://genome-preview.ucsc.edu). Visual browsing, data mining and download of raw and processed data files are all supported. An ENCODE portal (http://encodeproject.org) provides specialized tools and information about the ENCODE data sets.Keywords
This publication has 23 references indexed in Scilit:
- Mapping and analysis of chromatin state dynamics in nine human cell typesNature, 2011
- The NIH Roadmap Epigenomics Mapping ConsortiumNature Biotechnology, 2010
- BigWig and BigBed: enabling browsing of large distributed datasetsBioinformatics, 2010
- The Universal Protein Resource (UniProt) in 2010Nucleic Acids Research, 2009
- The Sequence Alignment/Map format and SAMtoolsBioinformatics, 2009
- NCBI Reference Sequences: current status, policy and new initiativesNucleic Acids Research, 2009
- BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammalsNature Methods, 2008
- Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot projectNature, 2007
- NCBI reference sequences (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteinsNucleic Acids Research, 2007
- NCBI GEO: mining tens of millions of expression profiles--database and tools updateNucleic Acids Research, 2006