APPLICATION OF LIVE ATTENUATED MEASLES AND MUMPS VACCINES IN CHILDREN WITH ACUTE-LEUKEMIA

  • 1 January 1981
    • journal article
    • research article
    • Vol. 24  (4) , 147-151
Abstract
Eight children with acute leukemia in remission were immunized with live attenuated measles vaccine and 4 with mumps vaccine. Immunological examinations before vaccination showed that the numbers of white blood cells, percentages of lymphocytes, levels of Ig and responses to skin tests with dinitrochlorobenzene, purified protein derivative, phytohemagglutinin and varicella antigen were within normal ranges in most of these children. Chemotherapy against leukemia was stopped for 2 wk, from 1 wk before to 1 wk after vaccination. One child had a transient fever 10 days after measles vaccination, but no side reactions were observed in the others. Seroconversion was observed in all but 1 child who received measles vaccine and neutralizing antibodies have persisted for at least 4 wk and at most 3 yr when this study was terminated.

This publication has 1 reference indexed in Scilit: