Abstract
An ultrastructural study of the adenohypophys is, after exposure of female Wistar rats to a signalled unpredictable 5 and 15 day stress regimen, is described. Cellular activity of the adenohypophysis correlated well with the circulating levels of corticosterone. Intense secretory activity was observed in all tropic cell types at 5 and 15 days although the observed differences generally were greater in the 5 day stressed group. The estrous cycles of 40 and 100% of the rats became desynchronized over the 5 and 15 day stress period, respectively.

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