Annular Protofibrils Are a Structurally and Functionally Distinct Type of Amyloid Oligomer

This publication has 50 references indexed in Scilit:

• Lipids revert inert Aβ amyloid fibrils to neurotoxic protofibrils that affect learning in mice
  The EMBO Journal, 2007
• Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers
  Molecular Neurodegeneration, 2007
• Amyloid beta ion channel: 3D structure and relevance to amyloid channel paradigm
  Biochimica et Biophysica Acta (BBA) - Biomembranes, 2007
• Atomic structures of amyloid cross-β spines reveal varied steric zippers
  Nature, 2007
• Soluble Amyloid Oligomers Increase Bilayer Conductance by Altering Dielectric Structure
  The Journal of general physiology, 2006
• Rationalization of the effects of mutations on peptide andprotein aggregation rates
  Nature, 2003
• Common Structure of Soluble Amyloid Oligomers Implies Common Mechanism of Pathogenesis
  Science, 2003
• Annular α-Synuclein Protofibrils Are Produced When Spherical Protofibrils Are Incubated in Solution or Bound to Brain-Derived Membranes
  Biochemistry, 2002
• Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases
  Nature, 2002
• Aggregation and secondary structure of synthetic amyloid βA4 peptides of Alzheimer's disease
  Journal of Molecular Biology, 1991