ECTOPIC BETA-HUMAN CHORIONIC-GONADOTROPIN PRODUCTION BY BLADDER UROTHELIAL NEOPLASIA

  • 1 February 1986
    • journal article
    • research article
    • Vol. 110  (2) , 107-111
Abstract
Endocrine manifestations are rarely observed in bladder urothelial neoplasia. To our knowledge, only 11 cases of choriocarcinoma have been reported in this site, and recently the production of .beta.-human chorionic gonadotropin has been demonstrated in these tumors by applying the immunoperoxidase technique. Of 104 transitional cell neoplasms of the bladder, we demonstrated by the indirect immunoperoxidase technique .beta.-human chorionic gonadotropin production in 12 neoplasms, 11 of which were grade 3 and 4 transitional cell carcinomas.