Use of Complement Fixation Screening Technique to Identify Poliovirus in Enterovirus Isolates

Abstract
Isolates from 980 fecal and rectal swab specimens were used as complement-fixing antigens and screened for the 3 types of poliovirus. Of these isolates, 726 (74%) were identified as type 1, 2, or 3 poliovirus. Twelve isolates, (1.2%) were incorrectly identified by complement fixation. Five of these isolates were subsequently found to be poliovirus, and 7 were shown to be Coxsackie B4 by neutralization test.