Chemistry of carbamoyl disulfide protected derivatives of proline*
- 1 March 1982
- journal article
- research article
- Published by Wiley in International Journal of Peptide and Protein Research
- Vol. 19 (3) , 321-324
- https://doi.org/10.1111/j.1399-3011.1982.tb03045.x
Abstract
High-yield methods were devised for the synthesis of a series of alkyl and aryldithiocarbonyl derivatives of the .alpha.-imino acid proline. The carbamoyl disulfide protecting groups were rapidly and quantitatively removed under a variety of reductive conditions, suggesting their potential value for orthogonal schemes of peptide synthesis.Keywords
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