The Alu Family of Dispersed Repetitive Sequences
- 4 June 1982
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 216 (4550) , 1065-1070
- https://doi.org/10.1126/science.6281889
Abstract
A family of related sequences that includes approximately 500,000 members is the most prominent short dispersed repeat family in primate and rodent DNA's. The primate sequence is approximately 300 base pairs in length and is composed of two imperfectly repeated monomer units, whereas the rodent repeat consists of only a single monomer. Properties of this repeat sequence, its flanking sequences in chromosomal DNA, and RNA's transcribed from it suggest that it may be a mobile DNA element inserted at hundreds of thousands of different chromosomal locations.Keywords
This publication has 54 references indexed in Scilit:
- Base sequence studies of 300 nucleotide renatured repeated human DNA clonesJournal of Molecular Biology, 1981
- Evolution of the β-globin gene cluster in man and the primatesJournal of Molecular Biology, 1981
- Selfish genes, the phenotype paradigm and genome evolutionNature, 1980
- Partial nucleotide sequence of the 300-nucleotide interspersed repeated human DNA sequencesNature, 1980
- A ubiquitous family of repeated DNA sequences in the human genomeJournal of Molecular Biology, 1979
- Inverted repetitive sequences in the human genomeBiochemistry, 1976
- An electron microscope study of the DNA sequence organization of the human genomeJournal of Molecular Biology, 1976
- Sequence organization in Xenopus DNA studied by the electron microscopeJournal of Molecular Biology, 1975
- Palindromes in chromosomesJournal of Molecular Biology, 1974
- Isolation of the complementary strands of a human satellite DNAJournal of Molecular Biology, 1968