Biocatalytic Preparation of Enantiomerically Pureendo-Bicyclo[3.3.0]oct-7-en-2-ol
- 1 January 1989
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1989 (12) , 933-934
- https://doi.org/10.1055/s-1989-27433
Abstract
(+)-endo-(1R,2R,5R)-Bicyclo[3.3.0]oct-7-en-2-ol (2) and its (-)-enantiomer, versatile building units for the synthesis of cyclopentanoid natural products, are prepared by enzymatic resolution of their racemic alkyl esters using Pseudomonas fluorescens lipase.Keywords
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