Estrus-Inducing Pheromone of Male Mice: Transport by Movement of Air

Abstract
The proportion of female SJL/J mice exhibiting estrus when placed 2 meters downwind (6 meters per minute) from a group of 15 hybrid males was not significantly less than that of females placed directly under the males and exposed to their urine. The proportion of mice showing estrus when placed 2 meters upwind was significantly less than that of mice downwind or of mice below males, but not different from that of females remote from males. These findings show that the pheromone from male mice is volatile and further support the concept that it acts through olfactory receptors.