Traceless Linking of Pyrroles: General Methology and Solid Phase Supported Functionalizations
- 28 January 2002
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 2002 (02) , 0274-0278
- https://doi.org/10.1055/s-2002-19813
Abstract
Transacetalization reaction of the diethoxymethyl (DEM) protected pyrroles 2a-f with the diol functionalized resin 3 resulted in the formation of the immobilized pyrroles 4a-f. Regioselective transformations including Pd-catalyzed coupling reactions and reductive aminations on solid phase were demonstrated.Keywords
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