In-vitro activity of Sch 34343 against anaerobic bacteria

Abstract
The in-vitro activity of Sch 34343, was compared with that of imipenem against 226 strains of anaerobic bacteria. Sch 34343 was identical in activity to imipenem, inhibiting 99.5% of the organisms tested at 16 mg/l (the breakpoint for both drugs). Imipenem was slightly more active than Sch 34343 against Bocteroides, Fusobacreriwn and Veilonella , although both drugs inhibited all organisms in these groups below breakpoint levels.

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