Carbon Dioxide Induced Acidosis in Pregnant Rats and Caries Susceptibility of Their Progeny

Abstract
Respiratory acidosis in the rat induced by exposure to 30% C02 in 70% 02 previous to the 10th day of gestation increased the severity of dental caries in the offspring subsequently fed a cariogenic skim milk diet. When applied after the 15th day of pregnancy it did not have any significant effect.