Studies on the Transfer of Immunity to Ascaris suum in Mice by Serum, Parabiotic Union, and Cells

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Abstract
Transfer of immunity to Ascaris suum larval infections was accomplished by parabiotic union of C57BL mice. A significantly lower worm burden after a challenge infection was found in the nonimmune partners of immune mice as compared to nonimmune partners of normal mice. Passive transfer of immunity by serum was attempted three times. In only a single experiment did injection of immune serum result in a decreased worm burden. An attempt was made to transfer immunity to ascaris larvae by peritoneal exudate cells and spleen cells. No significant difference in worm burden was found in the group of mice receiving cells from immunized donors as compared to that of control groups of mice.