Enantioselective Synthesis of Juvenile Hormone III in Three Steps from Methyl Farnesoate

Abstract
The asymmetric dihydroxylation of methyl farnesoate resulted in regioselective dihydroxylation of the 10, 11 olefin to give the (10S)and (10R) -(2E,6E)-10,11-dihydroxy-3,7,11-trimethyI-2,6-dodecadienoates in high ee. These diols were converted to juvenile hormone III and its enantiomer.

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